�Bayer HealthCare Pharmaceuticals, Inc. and Onyx Pharmaceuticals, Inc.
(Nasdaq: ONXX) announced the companies have begun enrolling patients
in the STORM Sorafenib as Adjuvant Treatment in the Prevention of
Recurrence of Hepatocellular Carcinoma trial. The randomized, double blind,
placebo-controlled Phase 3 sketch is evaluating Nexavar(R) (sorafenib)
tablets as adjuvant discussion, which is treatment next surgery or
local radiation, for patients with hepatocellular carcinoma (HCC), or
elemental liver cancer.
"Nexavar is the only systemic therapy with proven efficacy and
tolerability in HCC across multiple affected role populations," % 31, 2007,
filed with the Securities and Exchange Commission under the heading "Risk
Factors" and Onyx's Quarterly Reports on Form 10-Q for a more elaborated
description of such factors. Readers are cautioned not to situation undue
trust on these forward-looking statements that talk only as of the date
of this release. Onyx undertakes no obligation to update publicly whatever
forward-looking statements to reflect new information, events, or
circumstances afterwards the date of this release except as compulsory by law.
Nexavar(R) (sorafenib) tablets is a registered trademark of Bayer
HealthCare Pharmaceuticals, Inc.
References
(1) Ferlay J, et al., GLOBOCAN 2002. Cancer Incidence, Mortality and
Prevalence Worldwide. IARC CancerBase No.5, Version 2.0. IARCPress,
Lyon, 2004. Available at: hTTP://www-dep.iarc.fr. Accessed May 2008.
(2) 2005 Cancer Register System (CRS) annual report,
http://crs.cph.ntu.edu.tw/crs_c/annual.html. Accessed May 12, 2008.
(3) Del Pozo AC, Lopez P. Management of hepatocellular carcinoma. Clin
Liver Dis 2007 May;11(2):305-21.
Onyx Pharmaceuticals, Inc
http://www.onyx-pharm.com
View do drugs information on Nexavar.
More information
Wednesday, 27 August 2008
Thursday, 7 August 2008
Carmona
Artist: Carmona
Genre(s):
Other
Discography:
Lunares Pa Tu Vestio
Year: 2006
Tracks: 10
Yahari
Year: 2005
Tracks: 11
 
Smokey Robinson
Monday, 30 June 2008
AFTRA, producers head back to table
SAG members will meet for update Monday night
Talks between AFTRA and the AMPTP began May 7 following the suspension of negotiations with sister guild SAG. The two performers unions are negotiating the primetime TV contract separately for the first time in 27 years after a fallout on the eve of formal talks.
Not much has been released about the negotiations between AFTRA and the producers because of a news blackout. However, in an e-mail message to members last week, AFTRA president Roberta Reardon indicated that the two sides were making progress.
In the meantime, Los Angeles SAG members will meet Monday night to discuss the guild's recent contract talks and the state of the negotiation process. Talks between SAG and the AMPTP began April 15 and broke down May 6 with no new deal. The AMPTP has offered to meet with SAG on May 28, indicating that it expects to finish negotiations with AFTRA in the next week and a half.
In a video message to members posted last week on the union's Web site, SAG national executive director and chief negotiator Doug Allen said that the AMPTP suspended the negotiations "in spite of the progress we were making and moves we made in their direction."
Among the issues Allen said the two sides "spent quite a bit of time" discussing was product placement and integration in film and TV productions and "dealing with the circumstances that actors find themselves in when they're making scripted content but they're handed a product to extol or endorse.
"We've proposed language that says they should have the right to refuse to do that if they're not comfortable essentially making a commercial in the middle of scripted content," he added.
Allen said the union understands product placement is necessary to finance the production, but the actor should have the right to refuse to participate if they have an outside contract that might conflict with the product placement or simply do not want to do it.
He did not, however, indicate whether the two sides came to any sort of agreement on the issue.
Allen also indicated that there were "some boulders in the road," including the AMPTP's proposals to create an online clip library in which they want actors to give blanket consent for the use of legally downloaded content. While studios are allowed to use the clips for promotion, any further use requires approval from the actor, pursuant to the union's contract.
Allen said the AMPTP wants to get rid of that requirement and replace it with a completely unfettered agreement.
"We think that's a problem," he said.
As for the May 28 date offered by the AMPTP, SAG has accepted, but Allen said it's "wasting time" to have a date so far ahead and they should be talking tomorrow."
"We're prepared to go back to the table and get this deal done as soon as possible," he said, adding, "We need their cooperation. We can't do this by ourselves."
SAG's contract also expires June 30.
See Also
Wednesday, 25 June 2008
Castanets
Artist: Castanets
Genre(s):
Rock
Indie
Discography:
In the Vines
Year: 2007
Tracks: 10
What Kind of Cure
Year: 2005
Tracks: 11
First Light's Freeze
Year: 2005
Tracks: 13
Cathedral
Year: 2004
Tracks: 11
San Diego's Castanets take up from commonwealth, folk, and experimental rock and change state them into a effectual that's evenly helen Newington Wills and inspiring. The band, which features a revolving cast of supportive musicians (including members from Pinback, Rocket from the Crypt, and Tristeza), centers on singer/songwriter Raymond Raposa, wHO explored the U.S. for four age via Greyhound heap later testing extinct of high schooltime at age 15. This trenchant, traveling nature extends to his music, which he initially released as a series of CD-Rs. However, the Asthmatic Kitty mark stepped in and released his first-class honours degree widely available album, Cathedral -- the bulk of which was recorded in a cabin in northern California's woodlands -- in strike 2004. A year later, Raposa and company returned with First-class honours degree Light's Freeze. A period of acute depression followed, during which Raposa was mugged outside of his home in Bedstuy, Brooklyn. In the Vines, the Castanets' third waiver, was completed weeks after the mugging; appropriately benighted (but heartfelt yet), the record album was released in October 2007.
Kenny Rogers, Edson Hudson
Wednesday, 18 June 2008
The Buzzcocks
Artist: The Buzzcocks
Genre(s):
Other
Rock: Punk-Rock
Rock
Discography:
The Complete Singles Anthology (CD 3)
Year: 2004
Tracks: 10
The Complete Singles Anthology (CD 2)
Year: 2004
Tracks: 21
The Complete Singles Anthology (CD 1)
Year: 2004
Tracks: 24
Advance
Year: 2003
Tracks: 12
Beating Hearts Manchester '78
Year: 2001
Tracks: 19
BBC Sessions
Year: 1998
Tracks: 19
Operators Manual
Year: 1991
Tracks: 24
Live At The Roxy Club April...
Year: 1990
Tracks: 11
Singles Going Steady
Year: 1979
Tracks: 16
Peel Sessions
Year: 1979
Tracks: 14
Love Bites
Year: 1978
Tracks: 11
Another Music In A...
Year: 1978
Tracks: 11
Time's Up
Year: 1977
Tracks: 11
Orgasm Addict - Whatever 7
Year: 1977
Tracks: 4
Modern
Year:
Tracks: 14
Ever Fallen In Love
Year:
Tracks: 18
 
James McAvoy Denies Rumours of Lead Role in The Hobbit
Tuesday, 3 June 2008
Jesse Metcalfe - The Things They Say 8182
" I spent a fortune on a pair of green patent shoes once. It seemed like a good idea at the time now not so much..." Actor JESSE METCALFE admits to a major fashion faux pas.
See Also
Tuesday, 27 May 2008
Steve Earle keeps up the pace through summer
Steve Earle [ tickets ], who's been traveling across North America since February, has extended his tour through August.The Americana singer/songwriter is currently making his way from the Midwest to the East Coast, and will cross the Pond for a month-long European jaunt beginning May 15. He'll kick off the next leg of his North American tour June 27 in Tucson, AZ, and cross the US once again, with stops in a few Canadian provinces along the way. Domestic dates are included below and those overseas are listed at Earle's website.The performer's wife, singer Allison Moorer, opens the shows and joins Earle on stage during his set. DJ Neil McDonald is also traveling with the band, providing the beats heard on Earle's latest album, "Washington Square Serenade."In February, the set scored Earle his second Grammy Award for Best Contemporary Folk/Americana Album. "Washington Square Serenade," produced by John King of the Dust Brothers (Beck, Beastie Boys), marked a fresh start for Earle, as it was the first album he recorded since relocating to New York from Nashville, where he had based his career since 1975.The record, which the renegade musician has called "unapologetically personal," pays tribute to the '60s folk revival in New York City."That period changed pop music," Earle stated in his bio. "It made lyrics much more important. Rock and roll could have become a sub-genre of pop if it hadn't been for that literary aspect, which completely came out of a four-block area in New York City in one brief instant of time."
Tuesday, 20 May 2008
Sopranos star for Marvin Gaye film
Sopranos star for Marvin Gaye film
'The Sopranos' asterisk James Gandolfini has been cast opposition 'Law & Order' star Jesse L Martin in a new cinema about the last age of soul fable Marvin Gaye.
Smorgasbord reports that 'Sexual Healing' will account Gaye's (Dean Martin) self-imposed transportation in Kingdom of Belgium and his return to the big time with the aid of impresario Freddy Cousaert (Gandolfini).
The Lauren Goodman-directed photographic film will be produced by Gandolfini's company, Attaboy Films, and the worker will work as producer on the project.
Motion-picture photography of 'Sexual Healing' is due to begin on 15 Apr, with locations in Ostend, Massachuset and Los Angeles.
Friday, 2 May 2008
E Street Band member Danny Federici dies at 58
E Street Band member Danny Federici dies at 58
Freshly York - Danny Federici, the longtime keyboard player for Sir David Bruce Springsteen whose stylish make helped define the E Street Band’s sound on hits from "Hungry Pump" through "The Revolt," died Th. He was 58.
Federici, wHO had battled malignant melanoma for ternary years, died at Memorial Sloan-Kettering Crab Centre of attention in New House of York. Tidings of his death was posted tardily Th on Springsteen’s official Web web site.
He last performed with Springsteen and the band last month, coming into court during portions of a Marchland 20 evidence in Capital of Indiana.
"Danny and I worked together for 40 years _ he was the most wondrously fluid keyboard player and a pure natural musician. I loved him really a great deal ... we grew up in concert," Springsteen said in a argument posted on his Vane website.
Springsteen concerts scheduled for Friday in Fort Lauderdale, Fla., and Sat in Orlando were postponed.
Federici was max Born in Flemington, N.J., a long car ride from the Jersey shore haunts where he showtime met kindred musical theater emotional state Springsteen in the deep 1960s. The pair a great deal jammed at the Upstage Club in Asbury Ballpark, N.J., a now-defunct after hours club that hosted the best musicians in the state of matter.
It was Federici, along with master E Street Band drummer Vini Lopez, world Health Organization first-class honours degree invited Springsteen to join their band.
By 1969, the self-effacing Federici _ often introduced in concert by Springsteen as "Phantasm Dan" _ was playing with the Boss in a set called Child. Over the eld, Federici joined his champion in acclaimed set ashore bands Brand James Mill, Dr. Whizz and the Sonic Godsend and the Robert I Springsteen Band.
Federici became a stalwart in the E Street Band as Springsteen rocketed from the boardwalk to international stardom. Springsteen split up from the E Streeters in the late ’80s, but they reunited for a staggeringly successful circuit in 1999.
"Sir David Bruce has been supportive end-to-end my living," Federici said in a holocene question with Backstreets cartridge. "I’ve had my ups and downs, and I’ve sure enough precondition him a run for his money, and he’s always been at that place for me."
Federici played squeeze box on the wistful "4th Of July, Asbury Park (Sandy)" from Springsteen’s second album, and his organ solo was a highlight of Springsteen’s number one peak 10 hit, "Hungry Heart." His electric organ finale on the 9/11-inspired Springsteen song "You’re Missing" provided 1 of the to a greater extent heart-wrenching moments on "The Ascent" in 2002.
In a band with larger-than-life characters such as saxist Clarence Clemons and bandana-wrapped guitarist "Little" Steven Van Zandt, Federici was content to play in his familiar spirit position to the side of the leg. But his playing was as vital to Springsteen’s live show up as any instrumental role in the band.
Federici released a pair of solo albums that veered from the E Street sound and into soft jazz. Bandmates Nils Lofgren on guitar and Garry Tallent on bass joined Federici on his 1997 debut, "Flemington." In 2005, Federici released its follow-up, "Come out of the closet of a Aspiration."
Federici had taken a leave of absence during the band’s circuit in Nov 2007 to pursue treatment for melanoma, and was temporarily replaced by ex-serviceman instrumentalist Charles Giordano.
At the clock time, Springsteen described Federici as "one of the pillars of our sound and has played beside me as a great ally for more than 40 old age. We wholly thirstily await his healthy and speedy reelect."
Also his work with Springsteen, Federici played on albums by an impressive roster of other artists: Van Zandt, Joan Armatrading, Billy Graham Parker, Gary U.S. Bonds and Garland Jeffreys.
Wednesday, 30 April 2008
Ricci reveals struggle with anorexia
Ricci reveals struggle with anorexia
Hollywood star Christina Ricci has spoken virtually her struggle with anorexia as a teenager.
The actress admitted that she spent too much time obsessing over her appearing and that she was unable to savour her success whilst development up.
Ricci told US TV show Amusement Tonight: "I was a stripling sledding through adolescence and at one point I had a little anorexia phase and and so I sort of ballooned. I feel my body nowadays is the adult Christina and it's what I should experience issue forth to a long time ago if I hadn't been piece of ass about with my body so much.
"I was also occupy intellection about my cutis or my weight or the apparel I was wearing alternatively of just enjoying it and saying, 'I can't believe I become to be hither. This is awesome and I'm exit to receive it.'"
The 27-year-old added that she had now learned non to worry about her figure, expression: "The more weightiness you give your criticisms, the more it's departure to dissemble you. Dressing table is unnecessary.
"I'm the vainest person about merely I receive found a manner to let that go so I buns just have playfulness. You really take to make a decision in life that you're not sledding to be crippled by your insecurities."
Mary J Blige: Congratutions Jay-Z and Beyonce
Karen Matheson
Artist: Karen Matheson
Genre(s):
Celtic
Discography:
Time To Fall
Year: 2002
Tracks: 12
Capercailzie frontwoman Karen Matheson started playing at an other age. Performing at local greenwich Village halls in Scotland passim her younker, she would facilitate set about Tetrao urogallus with several high school school friends in the mid-80's. The dance orchestra had a successful vocation and released several albums passim the adjacent decades, but in 1997 Matheson distinct to examine her mitt at a solo spillage. The resulting album, The Dreaming Sea, showcased her outspoken range and gave her an prospect to experimentation with her talents. She rejoined the chemical group when they reconvened for their succeeding record record album, and stayed with them until 2002, when she decided to song some other solo album. Time to Fall, which was produced by Donald Artie Shaw and Paul McGeechan, appeared in the summer of that year.
Kylie Minogue wants more acting roles
Kylie Minogue wants more acting roles
Pop singer Kiley Minogue has reportedly expressed an interest in pursuing more performing projects in the close future.
The isaac Merrit Singer latterly recorded an installment of 'Doctor Who', with the show's administrator producer Russell T Davies later praising her.
Davies said: "She did this because I believe that's the way her thoughts ar bearing."
"She's missed it and fancied that discipline. I'd hurtle her once more like that. You forget that she has been in 'Neighbours', so she is used to knock come out of the closet an episode in a day."
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